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Protean

Protean Runtime—Real artifacts

Runtime
nervous system.

A sourced operating surface for Galen and the Protean runtime: live where artifacts exist, review-gated where operator confidence is required, and never biologically verified without a reviewed assay or publication source.

Snapshot generated

2026-06-03T05:46:52.147Z

Sources

12/13

Adapters

21/36

Candidates

8

Assay sources

0

Galen

Galen event feed

live log

runtime cycle

active

cognition-14-1780462069 · 20 candidates · 20 ranked · 0 review flags · 0 halt flags

2026-06-03T04:48:22.830Z · logs:runtime_events.jsonl

runtime cycle

observed

test-cycle-immutable · 50 candidates · 50 ranked · 0 review flags · 0 halt flags

2026-06-03T04:40:53.745Z · logs:runtime_events.jsonl

runtime cycle

observed

test-cycle · 50 candidates · 50 ranked · 0 review flags · 0 halt flags

2026-06-03T04:40:15.186Z · logs:runtime_events.jsonl

runtime cycle

observed

ingest-test · 0 candidates · 0 ranked · 16 review flags · 0 halt flags

2026-06-03T04:39:59.023Z · logs:runtime_events.jsonl

runtime cycle

observed

cog-test · 0 candidates · 0 ranked · 16 review flags · 0 halt flags

2026-06-03T04:39:58.935Z · logs:runtime_events.jsonl

runtime cycle

active

ingest-test · 0 candidates · 0 ranked · 0 review flags · 0 halt flags

2026-06-03T04:09:29.973Z · logs:runtime_events.jsonl

runtime cycle

observed

ingest-test · 0 candidates · 0 ranked · 1 review flags · 1 halt flags

2026-06-03T04:09:29.960Z · logs:runtime_events.jsonl

runtime cycle

active

ingest-test · 0 candidates · 0 ranked · 0 review flags · 0 halt flags

2026-06-03T04:09:29.890Z · logs:runtime_events.jsonl

runtime state transition

review gate

review-gated artifacts are present

2026-06-03T04:06:18Z · telemetry:state_transitions.jsonl

runtime_state

review gate

review-gated artifacts are present

2026-06-03T04:06:18Z · telemetry:events.jsonl

galen_status

review gate

Runtime event recorded

2026-06-03T04:06:18Z · telemetry:events.jsonl

galen status

observed

awaiting_review

2026-06-03T04:06:18Z · telemetry:events.jsonl

Graph

Operational flow

review gated
ingestionreview gate

Ingestion Sources

12 active source adapters

Count · 13 · ingestion:online_ingestion_status.json

evidenceactive

Evidence Index

764 provenance rows in latest cycle

Count · 764 · runtime:current_cycle_manifest.json

galenactive

Galen Reasoning

cognition-14-1780462069

Count · 12 · runtime:loop_status.json

scoringactive

Candidate Scoring

Dry-lab ranking; model outputs advisory only

Count · 8 · review:dry_lab_readiness_public_latest.json

reviewreview gate

Human Review

Review required before wet-lab execution or public release

Count · 8 · review:dry_lab_readiness_public_latest.json

wetlabprepared

Wet-Lab Handoff

Wet-lab automation disabled; packets are prepared for review

Count · 1 · wetlab:manifest.json

assayreview gate

Assay Feedback

Reviewed assay source gate

Count · 0 · candidate-results:ranking_snapshot_latest.json

memoryactive

Recursive Memory

12,063 recovery records rolled up

Count · 7 · memory:failure_rollup_latest.json

ledgeractive

Ledger / Mirror

Ledger is canonical; mirrors are supplemental

Count · 5 · research:protean-dossier-v1-reference.json

ingestion → evidencedata flow
evidence → galendata flow
galen → scoringdata flow
scoring → reviewdata flow
review → wetlabdata flow
wetlab → assaydata flow
assay → memorydata flow
memory → galendata flow
review → ledgerdata flow

Vercel

Cron heartbeat

heartbeat confidence

Galen local loop

local continuous loop

active

continuous_sleeping

Last output · 2026-06-03T04:48:22.830Z

Daily ingestion loop

86400s interval

observed

ingest-56-1780379315

Last output · 2026-06-02T06:03:47.152Z

Ledger indexer

* * * * *

active

Last public provenance export available; hosted job history awaits an output adapter.

Last output · 2026-06-03T05:31:08Z

Treasury snapshot

0 * * * *

source gate

Treasury cron is configured; output adapter pending.

Last output · not recorded

Mirror bridge

*/10 * * * *

active

Mirror bridge configured; local state exposes last published graph, not GitHub dispatch logs.

Last output · 2026-06-03T05:31:08Z

Scoring

Candidate pipeline

dry-lab only

Rank 1

GHQMQHHCDDSQPTDCWP

seqfam:4e57da74

review gate
Score
0.544
Band
low
Review
Needs human review
Family
seqfam:4e57da74
Sequence hash
sha256:4158ed1254a8...32b933
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 2

DCDQTNWPCGGQQHCDKA

seqfam:1d06061d

review gate
Score
0.529
Band
low
Review
Needs human review
Family
seqfam:1d06061d
Sequence hash
sha256:f38d64c05af2...4da676
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 3

WPIWQPHQTQCGSGGGC

seqfam:c72e48a6

review gate
Score
0.525
Band
low
Review
Needs human review
Family
seqfam:c72e48a6
Sequence hash
sha256:f1f03e5e69b1...63546a
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 4

HQMAQHCDDCDQFPTDCG

seqfam:7d29af0f

review gate
Score
0.521
Band
low
Review
Needs human review
Family
seqfam:7d29af0f
Sequence hash
sha256:ccbefd7a9142...dd338a
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 5

KPADSQHHNQNQRHHQW

seqfam:21d0d333

review gate
Score
0.505
Band
low
Review
Needs human review
Family
seqfam:21d0d333
Sequence hash
sha256:307a84b454e4...44e474
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 6

LPICKATQCGNQAKPVKA

seqfam:ac748a58

review gate
Score
0.502
Band
low
Review
Needs human review
Family
seqfam:ac748a58
Sequence hash
sha256:7c90672dc68c...936df3
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 7

VLPTQCGCTLPGWHQ

seqfam:79f0e998

review gate
Score
0.493
Band
low
Review
Needs human review
Family
seqfam:79f0e998
Sequence hash
sha256:b9318e2aff66...3508d9
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 8

GEMGYPFYHQEMGHQ

seqfam:150e1472

review gate
Score
0.486
Band
low
Review
Needs human review
Family
seqfam:150e1472
Sequence hash
sha256:532f6f5d2c73...c591ce
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Wet-lab

Wet-lab queue

Wet-lab automation disabled

Prepared, not submitted

cycle-20260526T020837Z-02-001

prepared

Auto-submit: disabled. Source: wetlab:manifest.json.

dossier.pdfmanifest.jsonprovenance.jsonreview charts

Adapters

Adapter coverage

review gate

Source catalog

AAindex amino acid property and substitution matricesactive
AlphaFold Protein Structure Databaseactive
BindingDB RESTful APIactive
bioRxiv / medRxiv APIactive
ChEMBL Data Web Servicesactive
ClinicalTrials.gov API v2active
Crossref REST APIactive
Curated peptide database adaptersactive
DailyMed RESTful APIactive
Europe PMC RESTful Web Serviceactive

Recent ingestion

uniprotactive

fresh 25 · cache 0

pubmedactive

fresh 25 · cache 0

europe_pmcactive

fresh 25 · cache 0

clinical_trialsactive

fresh 25 · cache 0

paperclipactive

fresh 25 · cache 0

fdaactive

fresh 25 · cache 0

crossrefactive

fresh 25 · cache 0

rcsb_pdbactive

fresh 25 · cache 0

Provenance

Ledger and mirror state

ledger canonical

GitHub artifact

protean-dossier-v1-reference

active

2026-06-01T17:35:04Z · research:protean-dossier-v1-reference.json

Basescan tx

0x4d1e526f...71be37

active

2026-06-01T17:35:04Z · research:protean-dossier-v1-reference.json

Inspect

IPFS package

bafybeihvfh6...vxmzqa

active

2026-06-01T17:35:04Z · research:protean-dossier-v1-reference.json

Inspect

Public graph export

71b554fd39...fc367d

active

2026-06-03T05:31:08Z · provenance:last_published_state.json

Inspect

Gitlawb mirror

proposal-first mirror adapter queued

source gate

not recorded · site-route:route.ts

Memory

Runtime memory

active

low total constraint

active

9,320

2026-06-03T04:48:23.384Z

terminated trial

active

750

2026-06-03T04:48:23.384Z

immunogenicity

active

658

2026-06-03T04:48:23.384Z

degradation

active

544

2026-06-03T04:48:23.384Z

enzymatic degradation

active

440

2026-06-03T04:48:23.384Z

poor solubility

active

217

2026-06-03T04:48:23.384Z

short half life

active

134

2026-06-03T04:48:23.384Z

Truthfulness

Source confidence

confidence gated

Assay confidence appears only when a reviewed assay or publication source is present. Wet-lab packets can be prepared, but submission and returned assay states require a source record.

Sources wired: Vercel cron configuration · Galen loop status · Telemetry JSONL · Full-sequence dry-lab readiness report · Ingestion status artifacts · Source catalog · Failure rollup · Public provenance and ledger artifact records.

source gatetreasury cron output adapter queued
source gateGitlawb mirror dispatch adapter queued
source gateassay feedback loop held at reviewed-source gate