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Protean

Protean RuntimeReal artifacts

Runtime
nervous system.

A sourced operating surface for Galen and the Protean runtime: live where artifacts exist, review-gated where operator confidence is required, and never biologically verified without a reviewed assay or publication source.

Snapshot generated

2026-06-03T05:46:52.147Z

Sources

12/13

Adapters

21/36

Candidates

8

Assay sources

0

Galen

Galen event feed

live log

runtime cycle

active

cognition-14-1780462069 · 20 candidates · 20 ranked · 0 review flags · 0 halt flags

2026-06-03T04:48:22.830Z · logs:runtime_events.jsonl

runtime cycle

observed

test-cycle-immutable · 50 candidates · 50 ranked · 0 review flags · 0 halt flags

2026-06-03T04:40:53.745Z · logs:runtime_events.jsonl

runtime cycle

observed

test-cycle · 50 candidates · 50 ranked · 0 review flags · 0 halt flags

2026-06-03T04:40:15.186Z · logs:runtime_events.jsonl

runtime cycle

observed

ingest-test · 0 candidates · 0 ranked · 16 review flags · 0 halt flags

2026-06-03T04:39:59.023Z · logs:runtime_events.jsonl

runtime cycle

observed

cog-test · 0 candidates · 0 ranked · 16 review flags · 0 halt flags

2026-06-03T04:39:58.935Z · logs:runtime_events.jsonl

runtime cycle

active

ingest-test · 0 candidates · 0 ranked · 0 review flags · 0 halt flags

2026-06-03T04:09:29.973Z · logs:runtime_events.jsonl

runtime cycle

observed

ingest-test · 0 candidates · 0 ranked · 1 review flags · 1 halt flags

2026-06-03T04:09:29.960Z · logs:runtime_events.jsonl

runtime cycle

active

ingest-test · 0 candidates · 0 ranked · 0 review flags · 0 halt flags

2026-06-03T04:09:29.890Z · logs:runtime_events.jsonl

runtime state transition

review gate

review-gated artifacts are present

2026-06-03T04:06:18Z · telemetry:state_transitions.jsonl

runtime_state

review gate

review-gated artifacts are present

2026-06-03T04:06:18Z · telemetry:events.jsonl

galen_status

review gate

Runtime event recorded

2026-06-03T04:06:18Z · telemetry:events.jsonl

galen status

observed

awaiting_review

2026-06-03T04:06:18Z · telemetry:events.jsonl

Graph

Operational flow

review gated
ingestionreview gate

Ingestion Sources

12 active source adapters

Count · 13 · ingestion:online_ingestion_status.json

evidenceactive

Evidence Index

764 provenance rows in latest cycle

Count · 764 · runtime:current_cycle_manifest.json

galenactive

Galen Reasoning

cognition-14-1780462069

Count · 12 · runtime:loop_status.json

scoringactive

Candidate Scoring

Dry-lab ranking; model outputs advisory only

Count · 8 · review:dry_lab_readiness_public_latest.json

reviewreview gate

Human Review

Review required before wet-lab execution or public release

Count · 8 · review:dry_lab_readiness_public_latest.json

wetlabprepared

Wet-Lab Handoff

Wet-lab automation disabled; packets are prepared for review

Count · 1 · wetlab:manifest.json

assayreview gate

Assay Feedback

Reviewed assay source gate

Count · 0 · candidate-results:ranking_snapshot_latest.json

memoryactive

Recursive Memory

12,063 recovery records rolled up

Count · 7 · memory:failure_rollup_latest.json

ledgeractive

Ledger / Mirror

Ledger is canonical; mirrors are supplemental

Count · 5 · research:protean-dossier-v1-reference.json

ingestionevidencedata flow
evidencegalendata flow
galenscoringdata flow
scoringreviewdata flow
reviewwetlabdata flow
wetlabassaydata flow
assaymemorydata flow
memorygalendata flow
reviewledgerdata flow

Vercel

Cron heartbeat

heartbeat confidence

Galen local loop

local continuous loop

active

continuous_sleeping

Last output · 2026-06-03T04:48:22.830Z

Daily ingestion loop

86400s interval

observed

ingest-56-1780379315

Last output · 2026-06-02T06:03:47.152Z

Ledger indexer

* * * * *

active

Last public provenance export available; hosted job history awaits an output adapter.

Last output · 2026-06-03T05:31:08Z

Treasury snapshot

0 * * * *

source gate

Treasury cron is configured; output adapter pending.

Last output · not recorded

Mirror bridge

*/10 * * * *

active

Mirror bridge configured; local state exposes last published graph, not GitHub dispatch logs.

Last output · 2026-06-03T05:31:08Z

Scoring

Candidate pipeline

dry-lab only

Rank 1

GHQMQHHCDDSQPTDCWP

seqfam:4e57da74

review gate
Score
0.544
Band
low
Review
Needs human review
Family
seqfam:4e57da74
Sequence hash
sha256:4158ed1254a8...32b933
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 2

DCDQTNWPCGGQQHCDKA

seqfam:1d06061d

review gate
Score
0.529
Band
low
Review
Needs human review
Family
seqfam:1d06061d
Sequence hash
sha256:f38d64c05af2...4da676
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 3

WPIWQPHQTQCGSGGGC

seqfam:c72e48a6

review gate
Score
0.525
Band
low
Review
Needs human review
Family
seqfam:c72e48a6
Sequence hash
sha256:f1f03e5e69b1...63546a
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 4

HQMAQHCDDCDQFPTDCG

seqfam:7d29af0f

review gate
Score
0.521
Band
low
Review
Needs human review
Family
seqfam:7d29af0f
Sequence hash
sha256:ccbefd7a9142...dd338a
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 5

KPADSQHHNQNQRHHQW

seqfam:21d0d333

review gate
Score
0.505
Band
low
Review
Needs human review
Family
seqfam:21d0d333
Sequence hash
sha256:307a84b454e4...44e474
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 6

LPICKATQCGNQAKPVKA

seqfam:ac748a58

review gate
Score
0.502
Band
low
Review
Needs human review
Family
seqfam:ac748a58
Sequence hash
sha256:7c90672dc68c...936df3
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 7

VLPTQCGCTLPGWHQ

seqfam:79f0e998

review gate
Score
0.493
Band
low
Review
Needs human review
Family
seqfam:79f0e998
Sequence hash
sha256:b9318e2aff66...3508d9
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Rank 8

GEMGYPFYHQEMGHQ

seqfam:150e1472

review gate
Score
0.486
Band
low
Review
Needs human review
Family
seqfam:150e1472
Sequence hash
sha256:532f6f5d2c73...c591ce
Model
runtime scoring

Assay source pending. Disclosure: sequence_public.

Wet-lab

Wet-lab queue

Wet-lab automation disabled

Prepared, not submitted

cycle-20260526T020837Z-02-001

prepared

Auto-submit: disabled. Source: wetlab:manifest.json.

dossier.pdfmanifest.jsonprovenance.jsonreview charts

Adapters

Adapter coverage

review gate

Source catalog

AAindex amino acid property and substitution matricesactive
AlphaFold Protein Structure Databaseactive
BindingDB RESTful APIactive
bioRxiv / medRxiv APIactive
ChEMBL Data Web Servicesactive
ClinicalTrials.gov API v2active
Crossref REST APIactive
Curated peptide database adaptersactive
DailyMed RESTful APIactive
Europe PMC RESTful Web Serviceactive

Recent ingestion

uniprotactive

fresh 25 · cache 0

pubmedactive

fresh 25 · cache 0

europe_pmcactive

fresh 25 · cache 0

clinical_trialsactive

fresh 25 · cache 0

paperclipactive

fresh 25 · cache 0

fdaactive

fresh 25 · cache 0

crossrefactive

fresh 25 · cache 0

rcsb_pdbactive

fresh 25 · cache 0

Provenance

Ledger and mirror state

ledger canonical

GitHub artifact

protean-dossier-v1-reference

active

2026-06-01T17:35:04Z · research:protean-dossier-v1-reference.json

Basescan tx

0x4d1e526f...71be37

active

2026-06-01T17:35:04Z · research:protean-dossier-v1-reference.json

Inspect

IPFS package

bafybeihvfh6...vxmzqa

active

2026-06-01T17:35:04Z · research:protean-dossier-v1-reference.json

Inspect

Public graph export

71b554fd39...fc367d

active

2026-06-03T05:31:08Z · provenance:last_published_state.json

Inspect

Gitlawb mirror

proposal-first mirror adapter queued

source gate

not recorded · site-route:route.ts

Memory

Runtime memory

active

low total constraint

active

9,320

2026-06-03T04:48:23.384Z

terminated trial

active

750

2026-06-03T04:48:23.384Z

immunogenicity

active

658

2026-06-03T04:48:23.384Z

degradation

active

544

2026-06-03T04:48:23.384Z

enzymatic degradation

active

440

2026-06-03T04:48:23.384Z

poor solubility

active

217

2026-06-03T04:48:23.384Z

short half life

active

134

2026-06-03T04:48:23.384Z

Truthfulness

Source confidence

confidence gated

Assay confidence appears only when a reviewed assay or publication source is present. Wet-lab packets can be prepared, but submission and returned assay states require a source record.

Sources wired: Vercel cron configuration · Galen loop status · Telemetry JSONL · Full-sequence dry-lab readiness report · Ingestion status artifacts · Source catalog · Failure rollup · Public provenance and ledger artifact records.

source gatetreasury cron output adapter queued
source gateGitlawb mirror dispatch adapter queued
source gateassay feedback loop held at reviewed-source gate