Summary
Public thesis/export asset thesis_e6f07d388d3d3492. Galen flagged a prioritization gap where high-ranked antimicrobial candidates can sit near degradation or instability failure signals without subgroup handling. The runtime proposed failure-correlation proximity as a discriminator separating rank-supported candidates from candidates with degradation-like behavior. Evidence shape stayed metric-heavy: Failure Correlation metric records aligned with CyclicMPNN and degradation;instability. Contradicting evidence was absent, so no record constrained the separation beyond low evidence strength and motif-level scope. The runtime weighted confidence at 0.76, tempered by evidence_strength 0.35 and uncertainty_score 0.16. The §8 panel should adjudicate whether proline-rich motifs PPGP, PGPP, and PPPG require separate assay routing. Boundary: public research artifact with explicit uncertainty, not biological validation.