{
  "figures": [
    {
      "alt": "Flow diagram of the computational study workflow ending in family clustering and DBAASP context.",
      "caption": "Study workflow from archived proteomes through deterministic filtering, candidate generation, family clustering, and DBAASP nearest-neighbor context.",
      "id": "figure-1-study-workflow",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-1-study-workflow.png",
      "source_artifacts": [
        "candidate_manifest.json",
        "family_manifest.json",
        "dbaasp_novelty_summary.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-1-study-workflow.svg"
    },
    {
      "alt": "Horizontal bar chart showing filtering counts: 58,449, 8,063, 1,394, 1,099, and 470.",
      "caption": "Filtering funnel from 58,449 predicted fungal proteins to 470 mature peptide candidates.",
      "id": "figure-2-filtering-funnel",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-2-filtering-funnel.png",
      "source_artifacts": [
        "candidate_statistics.json",
        "candidate_manifest.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-2-filtering-funnel.svg"
    },
    {
      "alt": "Grouped bar chart comparing cluster counts and singleton counts at 90, 80, and 70 percent identity.",
      "caption": "MMseqs2 clustering at 90%, 80%, and 70% identity. The 70% threshold defines 346 candidate families.",
      "id": "figure-3-cluster-collapse",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-3-cluster-collapse.png",
      "source_artifacts": [
        "cluster_report.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-3-cluster-collapse.svg"
    },
    {
      "alt": "Horizontal bar chart showing candidate counts for Gymnopilus dilepis, Panaeolus cyanescens, Psilocybe cubensis, and Psilocybe cyanescens.",
      "caption": "Species-level contribution to the 470 retained mature peptide candidates.",
      "id": "figure-4-species-contribution",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-4-species-contribution.png",
      "source_artifacts": [
        "candidate_manifest.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-4-species-contribution.svg"
    },
    {
      "alt": "Horizontal bar chart of recurring cysteine-spacing motifs and family counts.",
      "caption": "Top recurring cysteine-spacing motifs across 70% identity families.",
      "id": "figure-5-motif-family-distribution",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-5-motif-family-distribution.png",
      "source_artifacts": [
        "motif_analysis.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-5-motif-family-distribution.svg"
    },
    {
      "alt": "Bar chart showing DBAASP nearest-neighbor identity bins with most candidates between 50 and 69 percent identity.",
      "caption": "Nearest-neighbor identity distribution for 470 candidates against the local DBAASP corpus.",
      "id": "figure-6-dbaasp-identity-distribution",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-6-dbaasp-identity-distribution.png",
      "source_artifacts": [
        "dbaasp_candidate_neighbors.jsonl",
        "dbaasp_novelty_summary.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-6-dbaasp-identity-distribution.svg"
    },
    {
      "alt": "Horizontal bar chart of exact, 90, 80, 70, and 50 percent DBAASP nearest-neighbor thresholds.",
      "caption": "DBAASP nearest-neighbor threshold summary: no exact or >=90% identity matches were observed.",
      "id": "figure-7-reference-comparison-summary",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-7-reference-comparison-summary.png",
      "source_artifacts": [
        "dbaasp_novelty_summary.json"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-7-reference-comparison-summary.svg"
    },
    {
      "alt": "Grouped bar chart showing family cluster size and scaled DBAASP identity for top family representatives.",
      "caption": "Top family representatives by cluster size with DBAASP nearest-neighbor identity shown as identity times ten for scale.",
      "id": "figure-8-top-family-representatives",
      "png": "/research/studies/psilocybe-secretome-campaign/figures/figure-8-top-family-representatives.png",
      "source_artifacts": [
        "family_manifest.json",
        "dbaasp_family_neighbors.jsonl"
      ],
      "svg": "/research/studies/psilocybe-secretome-campaign/figures/figure-8-top-family-representatives.svg"
    }
  ],
  "generated_from_existing_artifacts_only": true,
  "schema": "protean.public-study-figures.v1",
  "study_slug": "psilocybe-secretome-campaign"
}